cysteine residue — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3088	N-Ethylmaleimide	1-Ethyl-1H-pyrrole-2,5-dione,Ethylmaleimide,NEM	Cysteine Protease , DUB
	N-Ethylmaleimide (NEM) is a sulfhydryl reagent that is widely used in experimental biochemical studies.		Cysteine Protease , DUB
T15735	Leptomycin B	CI 940,LMB	CRM1 , Antibiotic , Antifungal
	Leptomycin B (LMB) is a potent inhibitor of the nuclear export of proteins and is a potent antifungal antibiotic blocking the eukaryotic cell cycle. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a ...		CRM1 , Antibiotic , Antifungal
T17731L	CL2A-SN-38 DCA 1279680-68-0(free base)		Others
	CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibito...		Others
TP1358	Peptide M
	Peptide M is a synthetic Peptide, 50 aa, derived from streptococcus M protein, containing an additional c-terminal cysteine residue.
T82394	FLAG-Cys
	FLAG-Cys is a Flag peptide modified by the addition of a cysteine (Cys) residue, known to exhibit immunogenicity [1].
T17732	CL2A		Others
	CL2A is a pH-sensitive, cleavable PEG8- and triazole-containing PABC-peptide-mc linker, characterized by its ability to induce a bystander effect. It forms a disulfide bond with an antibody at a cysteine residue. Labetuz...		Others
T78634	2′-Thioadenosine	PD157432	EGFR
	2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM against ErbB-2. It achieves covalent inactivation of ErbB-1 through...		EGFR
T78949	AM841		Cannabinoid Receptor
	AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor. It diminishes forskolin-stimulated cAMP accumulation and slows gastroi...		Cannabinoid Receptor
T76545	Cys(Npys)-TAT (47-57)
	Cys(Npys)-TAT (47-57), a peptide fragment corresponding to the transduction domain of the TAT peptide, features an activated cysteine residue C and is capable of electrostatically interacting with plasmid DNA. Notably, T...
T83750	Melittin (C-Term Cysteine labeled) TFA	Mel-Cys
	Melittin (C-term cysteine labeled), a variant of the toxic bee venom peptide melittin featuring a cysteine residue at its C-terminus, effectively induces hemolysis in isolated human red blood cells at both endosomal and ...
T80362	Human α-Defensin 6
	Human α-Defensin 6, a 32-residue, cysteine-rich peptide, plays a crucial role in mucosal immunity by inhibiting bacterial invasion. It achieves this through the formation of ordered self-assembly fibrils and nanonets, wh...
T4413	Poseltinib
	Poseltinib is an orally active, selective, and irreversible Bruton's tyrosine kinase (BTK) inhibitor, exhibiting a half-maximal inhibitory concentration (IC 50) of 1.95 nM. It demonstrates 0.3, 2.3, and 2.4-fold greater ...
T17731	CL2A-SN-38		Others
	CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific ant...		Others
T63351	MS8511
	MS8511, a selective covalent irreversible inhibitor of G9a/GLP, targets a cysteine residue at the substrate binding site, displaying IC50 values of 100 nM (G9a) and 140 nM (GLP), alongside Kd values of 44 nM (G9a) and 46...
T70128	Olmutinib hydrochloride
	Olmutinib is a novel third-generation epidermal growth factor receptor (EGFR) mutation-specific tyrosine kinase inhibitor, used in the treatment of T790M mutation positive non-small cell lung cancer. Olmutinib covalently...
T80249	Epsilon-V1-2, Cys-conjugated		PKC
	Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor. It hampers εPKC functionality by obstructing its translocation and the phosphorylation of MARCKS, additionally pertur...		PKC